Apoptosis Reagents and Kits

Assays, reagents, kits, and other assorted products used to detect cellular apoptosis, determine the activity levels of caspase or cathepsin, or identify similar cellular activity.

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1,036 – 1,050 of 1,818 results

1,036

Abcam Human L3MBTL3 knockout HEK-293T cell lysate.

Human L3MBTL3 knockout HEK-293T cell lysate.

The product is subject to the following: Abcam Restricted Use Statement

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1,037

Abcam Human COL6A1 knockout HEK-293T cell lysate.

Human COL6A1 knockout HEK-293T cell lysate.

The product is subject to the following: Abcam Restricted Use Statement

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1,038

Abcam Human NDUFS3 knockout HEK-293T cell lysate.

Human NDUFS3 knockout HEK-293T cell lysate.

The product is subject to the following: Abcam Restricted Use Statement

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1,039

ELABSCIENCE

NC4019412 TUNEL IN SITU APOPTOSIS GREEN

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1,040

Abcam Human CAV1 (Caveolin-1) knockout HeLa cell lysate.

Human CAV1 (Caveolin-1) knockout HeLa cell lysate.

The product is subject to the following: Abcam Restricted Use Statement

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1,041

Abcam Human CASP8 (Caspase-8) knockout HeLa cell lysate.

Human CASP8 (Caspase-8) knockout HeLa cell lysate.

The product is subject to the following: Abcam Restricted Use Statement

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1,042

Cayman Chemical Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt), Purity: ≥95%, 1 mg

A composite of a non-selective caspase inhibitor and a cell-permeable hydrophobic sequence; a non-selective caspase inhibitor

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1,043

Abcam Z-Asp-CH2-DCB, caspase inhibitor, 50MG

MW 454.3 Da, Purity >98%. Irreversible, cell permeable broad-spectrum caspase inhibitor (IC₅₀ values are 1.1 and 4.1 μM for caspase-3 and caspase-6 respectively). Inhibits hypoxia-induced apoptosis. Shows anti-ischemic effects in vivo. .

The product is subject to the following: Abcam Restricted Use Statement

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1,044

AdipoGen RBN-2397

Chemical. CAS 2381037-82-5. Formula C20H23F6N7O3. MW 523.4. RBN-2397 is a potent NAD competitive small molecule inhibitor of PARP-7. RBN-2397 selectively inhibits PARP-7 and demonstrates >50-fold selectivity for inhibition of PARP-7 over all PARP family members as measured by biochemical assays. RBN-2397 inhibits PARP-7-dependent MARylation IC50 = 2nM in cell biochemical assay and inhibits cells proliferation in NCI-H1373 lung cancer cells IC50 = 20nM. By selectively inhibiting PARP-7 in tumor cells, RBN-2397 has been shown to directly inhibit cellular proliferation and restore Type I interferon signaling to stimulate an innate and adaptive antitumor immune response. Targeting cytosolic nucleic acid sensing pathways and the Type I interferon IFN response is an emerging therapeutic strategy being explored in oncology. The PARP family consists of seventeen enzymes that regulate fundamental biological processes including response to cellular stress.